Volume 8, Issue 3 (Summer 2019)
Arch Hyg Sci 2019, 8(3): 178-187 |
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Ghavibazou L, Hosseini-Vasoukolaei N, Enayati A A, Akhavan A A, Motevalli Haghi F, Arabi M, et al . Epidemiological Survey of Cutaneous Leishmaniasis in Mazandaran Province, Northern Iran. Arch Hyg Sci 2019; 8 (3) :178-187
URL: http://jhygiene.muq.ac.ir/article-1-421-en.html
URL: http://jhygiene.muq.ac.ir/article-1-421-en.html
Leila Ghavibazou1 
, Nasibeh Hosseini-Vasoukolaei * 1, Ahmad Ali Enayati1 , Amir Ahmad Akhavan2 , Farzad Motevalli Haghi3 , Mohsen Arabi4 , Mahmoud Fazeli-Dinan1 , Atie Shemshadian1
, Nasibeh Hosseini-Vasoukolaei * 1, Ahmad Ali Enayati1 , Amir Ahmad Akhavan2 , Farzad Motevalli Haghi3 , Mohsen Arabi4 , Mahmoud Fazeli-Dinan1 , Atie Shemshadian1
1- Department of Medical Entomology and Vector Control, Health Science Research Centre, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran
2- Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
3- Department of Community Medicine, Mazandaran University of Medical Sciences
4- Department of Community Medicine, Mazandaran University of Medical Sciences, Sari, Iran
2- Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
3- Department of Community Medicine, Mazandaran University of Medical Sciences
4- Department of Community Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Abstract: (3997 Views)
Background & Aims of the Study: Cutaneous leishmaniasis (CL) is considered one of
the most important human vector-borne diseases in Iran. The current study aimed to
determine some epidemiological aspects of cutaneous leishmaniasis in Mazandaran,
Northern Iran.
Materials and Methods: This descriptive study was conducted using the epidemiological
data, including demographic and clinical features collected from 379 patients diagnosed
with leishmaniasis in health centers affiliated to the Deputy for Health Center of
Mazandaran University of Medical Sciences within 2009-2017. The disease was
diagnosed based on clinical information and direct microscopic examination of the
samples. Data were analyzed in SPSS software using nonparametric Kruskal-Wallis and
Mann-Whitney U tests.
Results: A total number of 379 individuals were diagnosed with CL during a 9-year
period. Considering the population in Mazandaran, the incidence rate was reported as 1.27
per 100,000 population. It was also revealed that most of the cases of CL (n=279; 73.6%)
were males and the majority of patients (n=137; 36.1%) were in the 20-29 age group. In
addition, the majority of the ulcers were observed in hand (n=152; 26.7%) and foot
(n=129; 22.6%), respectively. Moreover, just one ulcer was spotted in most of the patients
(n=143; 37.7%). As the final note, the incidence was at the highest level during autumn in
November (n=61; 16.1%).
Conclusion: As evidenced by the obtained results, cutaneous leishmaniasis poses a
daunting challenge to the public health in Mazandaran. This disease can be attributed to
several factors, including agricultural activities, animal husbandry, and frequent national
and international holidaymakers' visits to the province. With this background in mind,
the results of the currents study could contribute greatly to the effective control of this
disease
Type of Study: Original Article |
Subject:
Epidemiology
Received: 2019/10/7 | Accepted: 2019/11/9 | Published: 2020/01/15
Received: 2019/10/7 | Accepted: 2019/11/9 | Published: 2020/01/15
References
1. Behravan M, Hajjaran H, Abadi A, Haghighi A, Rahbarian N, Amini A, et al. Cutaneous leishmaniasis
2. in suspected refereed patients to health centers of Varamin and determination of sand flies species during 2012-2013. Med J Tabriz Univ Med Sci Health Serv 2015;37:6-11. Link
3. Hosseini-Vasoukolaei N, Jeddi-Tehrani M, Akhavan AA. Salivary transcript expression profiles of Phlebotomus papatasi: Antigenic variation of phlebotomus papatasi salivary glands regarding some biological and environmental factors. 1st ed. Germany: LAP Lambert Academic Publishing; 2016. Link
4. Heydarpour F, Sari AA, Mohebali M, Shirzadi M, Bokaie S. Incidence and disability-adjusted life years (Dalys) attributable to leishmaniasis in Iran, 2013. Ethiop J Health Sci 2016;26(4):381-8. PMID: 27587936 [DOI:10.4314/ejhs.v26i4.10]
5. Veysi A ,Yaghoobi-Ershadi MR, Rassi Y, HosseiniVasoukolaei N, Jeddi-Tehrani M, Rezaee-Node A, et al. Rearing and biology of phlebotomus sergenti, the main vector of anthroponotic cutaneous Leishmaniasis in Iran. J Arthropod Borne Dis 2017;11(4):504-14. PMID: 29367927
6. Doroodgar A, Asmar M, Razavi MR, Doroodgar M. Identifying the type of cutaneous leishmaniasis in patients, reservoirs and vectors by RAPD-PCR in Aran & Bidgol district of Esfahan Province during 2006-7. Feyz 2009;13(2):141-6. Link
7. Mirzaei A, Rouhani S, Parvizi P. Detection and determination of Leishmania parasite in reservoir hosts of Leishmaniasis in Isfahan province using routine laboratory methods and molecular tools. Sci J Ilam Univ Med Sci 2014;22(1):7-15. Link
8. Alipour H, Darabi H, Dabbaghmanesh T, Bonyani M. Entomological study of sand flies (Diptera: Psychodidae: Phlebotominae) in Asalouyeh, the heartland of an Iranian petrochemical industry. Asian Pac J Trop Biomed 2014;4(Suppl 1):S242-5. PMID: 25183089 [DOI:10.12980/APJTB.4.2014C678]
9. Mohammadi Azni S, Rassi Y, Oshaghi MA,Yaghoobi Ershdi MR, Mohebali MR, Abai M. Determination of parasite species of cutaneous leishmaniasis using Nested PCR in Damghan--Iran, during 2008. J Gorgan Univ Med Sci 2011;13(1):59-65. Link
10. Hosseini-Vasoukolaei N, Mahmoudi AR, Khamesipour A, Yaghoobi-Ershadi MR, Kamhawi S, Valenzuela JG, et al. Seasonal and physiological variations of Phlebotomus papatasi salivary gland antigens in central Iran. J Arthropod Borne Dis 2016;10(1):39-49. PMID: 27047970
11. Sofizadeh A, Faraji Far AA, Cherabin M, Badiei F, Cherabin MO, Sarli J, et al. Cutaneous leishmaniasis in Gonbad Kavoos, North of Iran (2009-11): an epidemiological study. J Gorgan Univ Med Sci 2013;14(4):100-6. Link
12. Hosseini-Vasoukolaei N, Idali F, Khamesipour A, Yaghoobi-Ershadi MR, Kamhawi S, Valenzuela JG, et al. Differential expression profiles of the salivary proteins SP15 and SP44 from Phlebotomus papatasi. Parasit Vectors 2016;9(1):357. PMID: 27342811 [DOI:10.1186/s13071-016-1633-z]
13. Jahanifard E, Yaghoobi-Ershadi MR, Akhavan AA, Akbarzadeh K, Hanafi-Bojd AA, Rassi Y, et al. Diversity of sand flies (Diptera, Psychodidae) in southwest Iran with emphasis on synanthropy of Phlebotomus papatasi and Phlebotomus alexandri. Acta Trop 2014;140:173-80. PMID: 25159535 [DOI:10.1016/j.actatropica.2014.08.017]
14. Shirzadi MR, Esfahania SB, Mohebalia M, Ershadia MR, Gharachorlo F, Razavia MR, et al. Epidemiological status of leishmaniasis in the Islamic Republic of Iran, 1983-2012. East Mediterr Health J 2015;21(10):736-42. PMID: 26750164 [DOI:10.26719/2015.21.10.736]
15. Khajedaluee M, Yazdanpanah MJ, SeyedNozadi S, Fata A, Juya MR, Masoudi MH, et al. Epidemiology of cutaneous leishmaniasis in population covered by Mashhad University of Medical Sciences in 2011. Med J Mashhad Univ Med Sci 2014;57(4):647-54. Link
16. Ramezani Y, Mousavi SG, Bahrami A, Fereydooni M, Parsa N, Kazemi B. Epidemiological study of cutaneous leishmaniasis in Aran and Bidgol from April to September 2009. Feyz 2011;15(3):254-8. Link
17. Doroodgar A, Mahbobi S, Nemetian M, Sayyah M, Doroodgar M. An epidemiological study of cutaneous leishmaniasis in Kashan (2007-2008). Koomesh 2009;10(3):177-84. Link
18. Youssefi MR, Shojaei J, Jalahi H, Amoli SA, Ghasemi H, Javadian M. Prevalence of cutaneous leishmaniasis during 2010 in Mazandaran Province, Iran. Afr J Microbiol Res 2011;5(31):5790-2. Link [DOI:10.5897/AJMR11.528]
19. Jafari R, Mohebali M, Dehghan-Dehnoee A, Soleimani H, Akhavan A, Hajjaran H, et al. Epidemiological status of cutaneous Leishmaniasis in Bafgh City, Yazd province 2005. J Shahid Sadoughi Univ Med Sci 2007;15(2):76-83. Link
20. Hamzavi Y, Sobhi SA, Rezaei M. Epidemiological factors of cutaneous lieshmaniasis in patients reffered to health centers in Kermanshah province (2001-2006). J Kermanshah Univ Med Sci J 2009;13(2):151-61. Link
21. Kassiri H, Sharifinia N, Jalilian M, Shemshad K. Epidemiological aspects of cutaneous leishmaniasis in Ilam province, west of Iran (2000-2007). Asian Pac J Trop Dis 2012;2:S382-6. Link [DOI:10.1016/S2222-1808(12)60186-8]
22. HanafiBojd AA, YaghoobiErshadi MR, Zamani J, Barzekar A, Jafari R, PoorAbazari G. Epidemiologic aspects of cutaneaus leishmaniasis in Hajiabad, Hormozgan, Iran (2003). Hormozgan Med J 2006;10(1):63-70. Link
23. Talari SA, Vakili Z, Moshtaghi S. Prevalence of cutaneus leishmaniasis in Kashan, 1994-2000. Feyz 2003;7(2):71-6. Link
24. Mohamadi Azni S, Rassi Y, Oshaghi MA, Ershdi Y, Reza M, Mohebali M, et al. Fauna and monthly activity of sand flies at zoonotic cutaneous leishmanianisis focus in Damghan district, Semnan province (2008). Koomesh 2010;11(2):107-12. Link
25. Fakhar M, Mikaeili F, Hatam G, Habibi P, Karamian M, Motazedian M, et al. A molecular epidemiology survey of cutaneous leishmaniasis in patients referring to Parasitology Lab at Shiraz School of Medicine and the importance of PCR assay. J Jahrom Univ Med Sci 2010;8(1):2-6. Link [DOI:10.29252/jmj.8.1.2]
26. Mesgarian F, Rahbarian N, Mahmoudi Rad M, Hajaran H, Shahbaz F, Mesgarian Z, et al. Identification of Leishmania species isolated from human cutaneous Leishmaniasis in Gonbad-e-Qabus city using a PCR method during 2006-2007. Tehran Univ Med J 2010;68(4):250-6. Link
27. Rassi Y, Javadian E, Jalali M, Motazedian M, Vatndoost H. Investigation on zoonotic cutaneous leishm-aniasis, Southern Iran. Iran J Public Health 2004;33:31-5. Link
28. Almasi HA, Shirdare M, Emadi J, Esfandiari M, Pourmohammadi B, Hosseini S. Epidemiological study of cutaneous leishmaniasis in Marvdasht, Fars province, Iran. J North Khorasan Univ Med Sci 2012;3(4):15-23. Link [DOI:10.29252/jnkums.3.4.15]
29. Karami M, Doudi M, Setorki M. Assessing epidemiology of cutaneous leishmaniasis in Isfahan, Iran. J Vector Borne Dis 2013;50(1):30-7. PMID: 23703437
30. Tohidi F, Barghae A. Cutaneous leishmaniasis parasite identification via PCR in the infected areas in Golestan province. Knowl Health J 2012;6(2):26-31. Link
31. Saghafipour A, Vatandoost H, Zahraei-Ramazani AR, Yaghoobi-Ershadi MR, Jooshin MK, Rassi Y, et al. Epidemiological study on cutaneous leishmaniasis in an endemic area, of Qom province, central Iran. J Arthropod Borne Dis 2017;11(3):403-13. PMID: 29322057
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