Volume 7, Issue 4 (Autumn 2018)
Arch Hyg Sci 2018, 7(4): 282-287 |
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Shams S, Ghorbanalizadgan M, Minoii S, Shojaei S. Evaluation of Bacterial Infection of Burn Wounds in a Burn Center, Qom, Iran. Arch Hyg Sci 2018; 7 (4) :282-287
URL: http://jhygiene.muq.ac.ir/article-1-335-en.html
URL: http://jhygiene.muq.ac.ir/article-1-335-en.html
1- Cellular and Molecular Research Center, Qom University of Medical Sciences, Qom, IR Iran
2- Department of Bacteriology, Faculty of Medical Sciences, Baqiyatallah University, Tehran, Iran.
3- Burn Center, Nekoei Hospital Qom, Iran.
2- Department of Bacteriology, Faculty of Medical Sciences, Baqiyatallah University, Tehran, Iran.
3- Burn Center, Nekoei Hospital Qom, Iran.
Abstract: (3659 Views)
| Background & Aims of the Study: In spite remarkable progress in the anti-microbial treatment in the last 60 years and despite all the care in the health system, infectious diseases especially burn wound infection is a major problem and one of the most important causes of morbidity and mortality for burn patients. Certainly, the identification, review and updating of bacterial infections and their antibiotic resistances have an important role in the control, prevention, and correct treatment of burn patients. This study aimed to determine burn wounds and antibiotic resistance in patients hospitalized at the Nekoei Burn Center, Qom, Iran. Material & Methods: A cross-sectional study was performed on patients referred to a Burn Center in Qom, Iran, for a three-year period (from May 2012 to November 2014). After sampling, the identification of the isolates was done by conventional biochemical tests. Disk diffusion method was performed for testing antibiotic resistance according to CLSI guideline. Results: Among a total of 793 patients, 45 patients (19.82%) were positive culture. Pseudomonas aeruginosa was the most dominant microorganism in patients (66%), followed by coagulase-negative staphylococci (16%) and Staphylococcus aureus (12%). In the evaluation of antibiotic resistance, Pseudomonas aeruginosa showed the most resistant to ciprofloxacin (93.3%) and ceftriaxone (86.6%). Among the used antibiotics, meropenem and cephalexin had a better effect than other antibiotics. |
Type of Study: Original Article |
Subject:
Microbiology
Received: 2018/05/22 | Accepted: 2018/11/18 | Published: 2018/11/25
Received: 2018/05/22 | Accepted: 2018/11/18 | Published: 2018/11/25
References
1. 1. Park YJ, Lee HK. The Role of Skin and Orogenital Microbiota in Protective Immunity and Chronic Immune-Mediated Inflammatory Disease. Frontiers in immunology. 2017;8:1955. Link [DOI:10.3389/fimmu.2017.01955]
2. Abdallah F, Mijouin L, Pichon C. Skin Immune Landscape: Inside and Outside the Organism. Mediators of Inflammation. 2017;2017. Link. [DOI:10.1155/2017/5095293]
3. Rajbahak S, Shrestha C, Singh A. Bacteriological changes of Burn Wounds with time and their Antibiogram. Scientific World. 2015;12(12):70-6. Link. [DOI:10.3126/sw.v12i12.13601]
4. Chahine EB, Sucher AJ. Skin and soft tissue infections. PSAP. 2015;1:1-27. Link.
5. Huang G, Sun K, Yin S, Jiang B, Chen Y, Gong Y, et al. Burn Injury Leads to Increase in Relative Abundance of Opportunistic Pathogens in the Rat Gastrointestinal Microbiome. Frontiers in microbiology. 2017;8:1237. Link. [DOI:10.3389/fmicb.2017.01237]
6. Church D, Elsayed S, Reid O, Winston B, Lindsay R. Burn wound infections. Clinical microbiology reviews. 2006;19(2):403-34. Link. [DOI:10.1128/CMR.19.2.403-434.2006]
7. Srinivasan S, Vartak AM, Patil A, Saldanha J. Bacteriology of the burn wound at the Bai Jerbai Wadia hospital for children, Mumbai, India-A 13-year study, Part I-Bacteriological profile. Indian journal of plastic surgery: official publication of the Association of Plastic Surgeons of India. 2009;42(2):213. Link. [DOI:10.4103/0970-0358.59284]
8. Bowler P, Duerden B, Armstrong DG. Wound microbiology and associated approaches to wound management. Clinical microbiology reviews. 2001;14(2):244-69. Link. [DOI:10.1128/CMR.14.2.244-269.2001]
9. Gouma E, Batistatou A, Verginadis II, Simos YV, Kyros L, Hadjikakou SK, et al. The Healing Effect of Four Different Silver Complexes on Full-thickness Skin Burns in a Rat Model. In Vivo. 2015;29(1):55-63. Link.
10. Saeidinia A, Keihanian F, Lashkari AP, Lahiji HG, Mobayyen M, Heidarzade A, et al. Partial-thickness burn wounds healing by topical treatment: A randomized controlled comparison between silver sulfadiazine and centiderm. Medicine. 2017;96(9). Link. [DOI:10.1097/MD.0000000000006168]
11. Othman N, Babakir-Mina M, Noori CK, Rashid PY. Pseudomonas aeruginosa infection in burn patients in Sulaimaniyah, Iraq: risk factors and antibiotic resistance rates. The Journal of Infection in Developing Countries. 2014;8(11):1498-502. Link. [DOI:10.3855/jidc.4707]
12. Shariati A, Azimi T, Ardebili A, Chirani AS, Bahramian A, Pormohammad A, et al. Insertional inactivation of oprD in carbapenem-resistant Pseudomonas aeruginosa strains isolated from burn patients in Tehran, Iran. New microbes and new infections. 2018;21:75-80. Link. [DOI:10.1016/j.nmni.2017.10.013]
13. Bayram Y, Parlak M, Aypak C, Bayram İ. Three-year review of bacteriological profile and antibiogram of burn wound isolates in Van, Turkey. International journal of medical sciences. 2013;10(1):19. Link. [DOI:10.7150/ijms.4723]
14. Mohapatra S, Deb M, Agrawal K, Chopra S, Gaind R. Bacteriological profile of patients and environmental samples in burn intensive care unit: a pilot study from a tertiary care hospital. Indian Journal of Burns. 2014;22(1):62. Link. [DOI:10.4103/0971-653X.147010]
15. Macedo JLSd, Santos JB. Bacterial and fungal colonization of burn wounds. Memorias do Instituto Oswaldo Cruz. 2005;100(5):535-9. Link. [DOI:10.1590/S0074-02762005000500014]
16. Kassim A, Omuse G, Premji Z, Revathi G. Comparison of Clinical Laboratory Standards Institute and European Committee on Antimicrobial Susceptibility Testing guidelines for the interpretation of antibiotic susceptibility at a University teaching hospital in Nairobi, Kenya: a cross-sectional study. Annals of clinical microbiology and antimicrobials. 2016;15(1):21. Link. [DOI:10.1186/s12941-016-0135-3]
17. Shams S, Hashemi A, Esmkhani M, Kermani S, Shams E, Piccirillo A. Imipenem resistance in clinical Escherichia coli from Qom, Iran. BMC Res Notes. 2018;11(1):314. Link. [DOI:10.1186/s13104-018-3406-6]
18. Lister PD, Wolter DJ, Hanson ND. Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms. Clinical microbiology reviews. 2009;22(4):582-610. Link. [DOI:10.1128/CMR.00040-09]
19. Control CfD, Prevention. Antibiotic resistance threats in the United States, 2013: Centres for Disease Control and Prevention, US Department of Health and Human Services; 2013. Link.
20. Rezaei E, Safari H, Naderinasab M, Aliakbarian H. Common pathogens in burn wound and changes in their drug sensitivity. Burns. 2011;37(5):805-7. Link. [DOI:10.1016/j.burns.2011.01.019]
21. Forson O, Ayanka E, Olu-Taiwo M, Pappoe-Ashong P, Ayeh-Kumi P. Bacterial infections in burn wound patients at a tertiary teaching hospital in Accra, Ghana. Annals of burns and fire disasters. 2017;30(2):116. Link.
22. Bedard E, Prevost M, Deziel E. Pseudomonas aeruginosa in premise plumbing of large buildings. MicrobiologyOpen. 2016;5(6):937-56. Link. [DOI:10.1002/mbo3.391]
23. Blair JM, Webber MA, Baylay AJ, Ogbolu DO, Piddock LJ. Molecular mechanisms of antibiotic resistance. Nature Reviews Microbiology. 2015;13(1):42. Link. [DOI:10.1038/nrmicro3380]
24. Džidić S, Šušković J, Kos B. Antibiotic resistance mechanisms in bacteria: biochemical and genetic aspects. Food Technology & Biotechnology. 2008;46(1). Link.
25. Weinstein RA, Mayhall CG. The epidemiology of burn wound infections: then and now. Clinical Infectious Diseases. 2003;37(4):543-50. Link. [DOI:10.1086/376993]
26. Lambert P. Mechanisms of antibiotic resistance in Pseudomonas aeruginosa. Journal of the royal society of medicine. 2002;95(Suppl 41):22. Link.
27. Hare NJ, Solis N, Harmer C, Marzook NB, Rose B, Harbour C, et al. Proteomic profiling of Pseudomonas aeruginosa AES-1R, PAO1 and PA14 reveals potential virulence determinants associated with a transmissible cystic fibrosis-associated strain. BMC microbiology. 2012;12(1):16.Link. [DOI:10.1186/1471-2180-12-16]
28. Ranjbar R, Owlia P, Saderi H, Mansouri S, Jonaidi-Jafari N, Izadi M, et al. Characterization of Pseudomonas aeruginosa strains isolated from burned patients hospitalized in a major burn center in Tehran, Iran. Acta Medica Iranica. 2011;49(10):675-9. Link.
29. Sorkh MAG, Shokoohizadeh L, Rashidi N, Tajbakhsh E. Molecular Analysis of Pseudomonas aeruginosa Strains Isolated from Burn Patients by Repetitive Extragenic Palindromic-PCR (rep-PCR). Iranian Red Crescent Medical Journal. 2017;19(4). Link. [DOI:10.5812/ircmj.43508]
30. Biswal I, Arora BS, Dimple Kasana N. Incidence of multidrug resistant pseudomonas aeruginosa isolated from burn patients and environment of teaching institution. Journal of clinical and diagnostic research: JCDR. 2014;8(5):DC26. Link
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