Epidemiological aspects and therapeutic outcomes of cutaneous leishmaniasis patients in Central Iran

Saghafipour, Abedin; Nejati, Jalil; Zahraei-Ramazani, Alireza; Vatandoost, Hassan; Mozaffari, Ehssan; Rezaei, Fatemeh

doi:10.29252/ArchHygSci.7.2.65

Volume 7, Issue 2 (Spring 2018 2018) Arch Hyg Sci 2018, 7(2): 65-70 | Back to browse issues page

‎ 10.29252/ArchHygSci.7.2.65

‎ 20.1001.1.22519203.2018.7.2.5.0

Mendeley

Zotero

RefWorks

Saghafipour A, Nejati J, Zahraei-Ramazani A, Vatandoost H, Mozaffari E, Rezaei F. Epidemiological aspects and therapeutic outcomes of cutaneous leishmaniasis patients in Central Iran. Arch Hyg Sci 2018; 7 (2) :65-70
URL: http://jhygiene.muq.ac.ir/article-1-260-en.html

Epidemiological aspects and therapeutic outcomes of cutaneous leishmaniasis patients in Central Iran

Abedin Saghafipour ^*

¹, Jalil Nejati²

, Alireza Zahraei-Ramazani³

, Hassan Vatandoost³

, Ehssan Mozaffari³

, Fatemeh Rezaei⁴

1- Department of Public Health, Faculty of Health, Qom University of Medical Sciences, Qom, Iran.
2- Zahedan University of Medical Sciences
3- Tehran University of Medical Sciences
4- Jahrom University of Medical Sciences, Jahrom, Iran

Abstract: (3585 Views)

Background & Aims of the Study: Cutaneous leishmaniasis (CL) is one of the re-emerging diseases in many areas of the Eastern Mediterranean region such as Iran. This study was conducted in order to detect the epidemiological aspects and therapeutic outcomes of CL patients in Kahakcounty, Qom province of Iran.
Materials & Methods: In this cross sectional study, clinical diagnosis of the disease was performed, using microscopic observation of the leishmania genus parasite in the ulcer site during 2016. Patients' data of therapeutic outcomes was recorded in epidemiological form of CL. Statistical analysis was done, using SPSS Ver. 16. Chi square and Fisher’s exact test were utilized for the assessment of the hypothesis.
Results: From 45 patients, 24 cases (53.3%) were men and 21 (46.7%) were women. Mean age of patients was 29.5 ±19.44. More than 28 % of samples were under 15 years old. The most common locations of ulcer in patient’s bodies were hands and feet (78.7%). 20.6% of samples had 3 ulcers and more. The highest prevalence of CL was happened in autumn. All of treated patients fully recovered without delays in treatment, complication or treatment failure.

Conclusions: CL disease has an endemic cycle in villages of Kahak County of Qom province and recently, prevalence of disease has been developing in this region, therefore, we proposed provincial health center staffs must design and implement suitable prevention programs based on health ministry guidelines in order to control of disease. Also, it seems Glucantime is the best and available drug for treating of this disease.

Keywords: Cutaneous leishmaniasis, Epidemiology, Treatment, Qom, Iran

Full-Text [PDF 407 kb] (939 Downloads) | | Full-Text (HTML) (639 Views)

Type of Study: Original Article | Subject: Epidemiology
Received: 2018/01/17 | Accepted: 2018/04/28 | Published: 2018/05/1

References

1. 1. Hotez PJ, Savioli L, Fenwick A. Neglected Tropical Diseases of the Middle East and North Africa: Review of Their Prevalence, Distribution, and Opportunities for Control. J Antimicrob. 2010; 6(2): 1-8 [DOI:10.1371/journal.pntd.0001475]

2. WHO. Working to overcome the global impact of neglected diseases. First WHO report on neglected tropical diseases. 2010; Geneva, Switzerland.

3. WHO. TDR Strategic Direction for Research: Leishmaniasis. Available at: www.who.int/tdr . 2002; Geneva, Switzerland.

4. Islamic Republic of Iran Ministry of Heath &Medical Education. Principles of disease prevention and surveillance. Tehran: Center for disease control. 2008: 249-255.

5. Akhavan AA, Yaghoobi-Ershadi MR, Mehdipour D, Abdoli H, Farzinnia B, Mohebali M, Hajaran H. Epidemic Outbreak of Cutaneous Leishmaniasis Due to Leishmania major in Ghanavat Rural District, Qom province, Central Iran. Iranian J Publ Health 2003; 32(4): 35-41

6. Islamic Republic of Iran. Weather Meteorological Organization. http://www.weather.ir

7. Jafari R, Mohebali M, Dehghan Dehnavi A, Soleimani H, Akhavan AA, Hajaran H, The epidemiology of cutaneous Leishmaniosis in Bafgh city Yazd province. J Yazd Uni Med Sci. 2007; 15(2): 76-83.

8. Rafati N, Shaporimoghadem A, Ghorbani R. Epidemiological study of cutaneous leishmaniasis in Damghan (2000-2006). J Semnan Uni Med Sci. 2007; 24(4): 250-51.

9. Sharifi I, Zamani F, Aflatoonian MR, Fekri AR. An Epidemic of Cutaneous Leishmaniasis in Baft District in Kerman province and its Probable Causative Risk Factors. Iranian J Epidemiology (IJE). 2008; 4(1): 53-58.

10. Mohajery M, Shamsian SA, Rezaee AR, Hassanpoor K, Shakeri MT, Farnoosh GH, Fathi Moghadam F. Evaluation of Mulecular Epidemiology of cutaneous leishmaniasis in Sabzevar. J Mashhad Uni Med Sci. 2010 53(3): 138-144.

11. Mohammadi Azni S, Nokandeh Z, Khorsandi A A, Sanei Dehkordi AR. Epidemiology of cutaneous leishmaniasis in Damghan district. Iranian J Military Med. 2010; 12(3): 131-135.

12. Hamzavi Y, Sobhi SA, Rezaee M. Epidemiological factors of cutaneous lieshmaniasis in patients referred to health centers in Kermanshah Province (2001 - 2006). J Behbood. 2009; 13(2): 155-56.

13. Rassi Y, Sofizadeh A, Abai MA, Oshaghi MA, Rafizadeh S, Moheba M, Mohtarami F, Salahi R. Molecular Detection of Leishmania major in the Vectors and Reservoir Hosts of Cutaneous Leishmaniasis in Kalaleh District, Golestan province, Iran. Iranian J Arthropod-Borne Dis. 2008; 2(2): 21-27

14. Zahirnia AH, Moradi AR, Norozi NA, Bathaii JN, Erfani H, Moradi A. Epidemiological Survey of Cutaneous Leishmaniasis in Hamadan province (2002-2007). J Hamadan Uni Med Sci. 2009; 16(1): 43-44.

15. Nazari M. Cutaneous leishmaniasis in Hamadan, Iran (2004-2010). J Zahedan Med Sci Res. 2012; 13 (9): 39-42 [DOI:10.1016/j.ijid.2012.05.442]

16. Hanafi Bojd AA, Yaghoobi Ershadi MR, Zamani Gh, Barzekar A, Jafari R, Poor Abazari Gh.R. Epidemiologic aspects of cutaneaus Leishmaniasis Hajiabad, Hormozgan, Iran, 2003. J Hormozgan Uni Med Sci. 2006; 10(1): 64-5.

17. Yaghoobi-Ershadi MR (1994). Study of current statue of cutaneous leishmanisis epidemiology in parts of Isfahan focuses for design and proposal control programme. [PhD Dissertation]. School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

18. Saghafipour A (2010) Study on some epidemiological characters of Cutaneous Leishmanianisis in Qomroud district. Qom province 2009-2010. [MSPH Dissertation]. School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

19. Yaghoobi-Ershadi MR, MarviiMoghadam N, Akhavan AA, Solaimani H, Zahraei-Ramazani AR, Arandian MH, Deghani-Dehnavi AR. The epidemiology of cutaneous Leishmaniosis a new focus of Khatam city, Yazd province. J Yazd Uni Med Sci. 2007; 15(4): 47-52.

20. Mesgarian F, Rahbarian N, Mahmoudi Rad M, Hajaran H, Shahbaz F. Identification of Leishmania species isolated from human cutaneous Leishmaniasis in Gonbad-e-Qabus city using a PCR method during 2006-2007. J Tehran Uni Med. 2010 68 (4): 250-256.

21. WHO. Control of the leishmaniasis, Report of a WHO Expert committee. 1990; Technical Report Series. 793. Geneva, Switzerland.