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Background & Aims of the Study: The Sharp Injuries (SIs) are a percutaneous piercing wound caused by a sharp instrument. Needle Sticks and Sharp Injuries (NSSIs) can increase the incidence of cases of Hepatitis B, C and HIV. The purpose of this study was to Investigation of the relative frequency of NSSIs in healthcare workers (HCWs) in Ahvaz, Iran (Razi hospital) over 3-year period (2011–2013).

Materials and Methods: A descriptive study during 2011-2013 was conducted on 600 HCWs at Razi Hospital, Ahvaz, Iran. To measure NSSIs, has been diagnosis and categorized based on the National Nosocomial Infections Surveillance (NNIS). Data about health workers’ age, sex, site of NSIs injury, ward of hospitalization and case of needle stick were collected. Descriptive statistical by SPSS version 16 used for analyzed data in this study.

Results: According to the results of this study, among all nurses, the maximum cases of NSIs were HCWs. Regarding the finding, recapping needle were found in 34.17%, handling needle in 20.25%, suturing in 16.45%, passing needle in 13.92%, transit disposal in 8.86% and dissembling needle in 6.32% of cases. Findings showed that the most NSIs in Razi Hospital were general surgery, emergency, Intensive Care Unit (ICU), Obstetrics and Gynecology (OBGYN), operating room, orthopedic and infectious diseases wards during 2011-2013.