Volume 12, Issue 3 (Summer 2023)
Arch Hyg Sci 2023, 12(3): 130-136 |
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Soori M, Nejad Ghaffar B Z, Abbaspour H, Hashemi-Moghaddam H, Moradi R. Investigation of Antioxidant and Antibacterial Effect of Chemical Compounds Cardamine uliginosa Plant. Arch Hyg Sci 2023; 12 (3) :130-136
URL: http://jhygiene.muq.ac.ir/article-1-654-en.html
URL: http://jhygiene.muq.ac.ir/article-1-654-en.html
Maryam Soori1 
, Bibi Zahra Nejad Ghaffar2 , Hossein Abbaspour3 , Hamid Hashemi-Moghaddam4 , Reza Moradi * 5
, Bibi Zahra Nejad Ghaffar2 , Hossein Abbaspour3 , Hamid Hashemi-Moghaddam4 , Reza Moradi * 5
1- Department of Biochemistry, Hamedan Branch, Islamic Azad University, Hamedan, Iran
2- Department of Biochemistry, Shoushtar Branch, Islamic Azad University, Shoushtar, Iran
3- Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran
4- Department of Chemistry, Damghan Branch, Islamic Azad University, Damghan, Iran
5- Department of Chemistry, Tuyserkan Branch, Islamic Azad University,Tuyserkan, Iran
2- Department of Biochemistry, Shoushtar Branch, Islamic Azad University, Shoushtar, Iran
3- Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran
4- Department of Chemistry, Damghan Branch, Islamic Azad University, Damghan, Iran
5- Department of Chemistry, Tuyserkan Branch, Islamic Azad University,Tuyserkan, Iran
Abstract: (499 Views)
Background & Aims: Brassicaceae is a medium-sized family of flowering plants. The family contains more than 327 genera. Cardamine uliginosa is a type of plant of this species. Chemical and biochemical findings of this genus are very limited. This study aimed to investigate the chemical compounds and antioxidant and antibacterial properties of C. uliginosa.
Materials and Methods: Essential oil was prepared by hydrodistillation method and microwave assisted hydrodistillation (MAHD). The chemical composition of essential oil was evaluated by GC and GC-MS methods. The antioxidant property of the hydroalcoholic extract was investigated by 2, 2-dipheny1-1-picrylhydrazyl (DPPH) solution. Finally, the antibacterial activity of C. uliginosa was investigated using minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) methods.
Results: Phetalic acid, Phenil, Caryophyllene, Eicosane, and other chemical compounds were found in the essential oil of C. uliginosa. The half maximum inhibitory concentration (IC50) of hydroalcoholic extract was 0.42 μg/mL. The MIC and the MBC against both Escherichia coli and Staphylococcus aureus were 15.62 and 31.25 respectively. The major compounds in the essential oils were 3-methyl-4-isopropylphenol (15.20%) and 1, 2-benzenedicarboxylic acid (16.75%).
Conclusion: Considering the chemical compounds of C. uliginosa and the finding of the antibacterial and antioxidant activity of C. uliginosa in vitro, capability of this plant needs to be further investigated for use in health and medical industries.
Materials and Methods: Essential oil was prepared by hydrodistillation method and microwave assisted hydrodistillation (MAHD). The chemical composition of essential oil was evaluated by GC and GC-MS methods. The antioxidant property of the hydroalcoholic extract was investigated by 2, 2-dipheny1-1-picrylhydrazyl (DPPH) solution. Finally, the antibacterial activity of C. uliginosa was investigated using minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) methods.
Results: Phetalic acid, Phenil, Caryophyllene, Eicosane, and other chemical compounds were found in the essential oil of C. uliginosa. The half maximum inhibitory concentration (IC50) of hydroalcoholic extract was 0.42 μg/mL. The MIC and the MBC against both Escherichia coli and Staphylococcus aureus were 15.62 and 31.25 respectively. The major compounds in the essential oils were 3-methyl-4-isopropylphenol (15.20%) and 1, 2-benzenedicarboxylic acid (16.75%).
Conclusion: Considering the chemical compounds of C. uliginosa and the finding of the antibacterial and antioxidant activity of C. uliginosa in vitro, capability of this plant needs to be further investigated for use in health and medical industries.
Type of Study: Original Article |
Subject:
Biochemistry
Received: 2023/02/14 | Accepted: 2023/05/6 | Published: 2023/10/2
Received: 2023/02/14 | Accepted: 2023/05/6 | Published: 2023/10/2
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